Hops and Xanthohumol

In addition to its remarkable contribution to the brewing process, hops have been used for medicinal purposes since medieval times. It is only at the beginning of the 20th century, however that scientists isolated its active ingredient : xanthohumol. 

Since then, scientific research has identified its numerous health enhancing properties and demonstrated xanthohumol’s many applications in boosting the body’s defences in the face of illness and the ravages of time. 

Only the best hops produce significant amounts of xanthohumol. The most advanced horticultural research has now begun to focus on the selective breeding of hops strains that are outstandingly rich in xanthohumol. 

A discovery that could change the world

XAN Extract

After some 50 years of research on several continents, three scientists at the prestigious Technical University of Munich had a break-through : they manage to stabilise volatile xanthohumol in a natural process. 

This consists of the simple admixing of xanthohumol with roast malt extract. Finally, consumers can access xanthohumol’s extraordinary health-boosting properties.?In order to deliver its health benefits, it is possible to add XAN Extract to foods, beverages and dietary supplements. 

Tonio Arcaini, founder and owner of TA-XAN, learnt of this discovery and quickly recognised the potential of xanthohumol for human health. From that his vision emerged for xanthohumol: to make an important contribution to health management, disease prevention and well-being. 

In 2019, Tonio Arcaini appointed Dr. Alexander Clauer, a consumer goods expert with 20 years of international experience in senior management roles in the beverage industry as CEO. 

XAN Extract – the only natural method of stabilising xanthohumol – is patent protected in over 50 counties. 

Stabilisation of Xanthohumol

The remarkable XAN Extract is produced in a patented process by admixing xanthohumol with roast malt extract. 

  • XAN Extract protects volatile xanthohumol from environmental influences such as heat and light – and this entirely thanks to its patented production process 
  • XAN Extract allows, for the first time, for the addition of xanthohumol to clear liquids, solid food and dietary supplements – a «first» after some 60 years of research worldwide 
  • XAN Extract unique production process significantly enhances the bio-availability of xanthohumol 

The production of XAN Extract requires only one basic processing technology and is to any extent scalable. Therefore, the supply of the patented XAN Extract can be adapted to customer requirements and sourced locally. 

XAN Extract – tapping into nature’s bounty


English scientists isolate xanthohumol as the active component of hops


on-going research into xanthohumol (decoding its structure, classification of its properties)


scientific proof of xanthohumol’s manifold health benefits


Professor Back at the Technical University of Munich, Germany, identifies the full scope of xanthohumol’s anti-oxidant effects. Xanthohumol is highly volatile and loses its health-boosting properties during processing – e.g. brewing


researchers at that same university finally come up with a method of stabilising xanthohumol. For the first time, it becomes possible to use XAN Extract as a carrier for the health-enhancing active agent xanthohumol


Tonio Arcaini, founder and owner of TA-XAN, formulates his health vision after a visit to DKFZ Heidelberg where Dr. Frank presented research on the prevention of major diseases


The company TA-XAN AG was established in Germany to implement Tonio Arcaini’s health vision for xanthohumol


TA-XAN commissioned a series of clinical trials in different parts of the world to determine the scientific proof of XAN Extract’s health benefits


First clinical trial completed by Medical University Vienna, proving the health benefits of XAN Extract.


Oregon state university confirms in a second clinical trial the unique health benefits and excellent bioavailability of XAN Extract.


FDA (US Food & Drug Administration) sanctions the health claim “DNA protection” for XAN Extract


TA-XAN submits the health claim “DNA protection” with EFSA (European Food Safety Authority)


TA-XAN commissions two additional clinical trials with larger subject groups and longer intervention periods to adduce final proof of DNA protection and the mitigation of metabolic syndrome


Two clinicial trials clearly prove that XAN Extract can address Metabolic Syndrome. XAN Extract significantly reduces blood sugar and hence can help all pre-diabetics and diabetics – thus mankind will no longer be hostage to diabetes.